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glutathione peroxidases in liver The peroxidase family: Discoveries and mechanism Molecular Medicine Reports

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Prolonged ER stress and activation of the unfolded protein response (UPR) contribute to macrophage apoptosis as substantiated by studies showing that apoptosis and the UPR effector, CHOP, increase with each stage of atherosclerosis in humans, but the largest increase is observed in the vulnerable plaque (175)

glutathione peroxidases in liver The peroxidase family: Discoveries and mechanism Molecular Medicine Reports

doi: 10.1002/cbdv.200490079

glutathione peroxidases in liver The peroxidase family: Discoveries and mechanism Molecular Medicine Reports

In some people, the infection becomes active again later in life, causing a painful, blistering rash called shingles

glutathione peroxidases in liver The peroxidase family: Discoveries and mechanism Molecular Medicine Reports

This "envelope" shields the glutathione from stomach acid and digestive enzymes

glutathione peroxidases in liver The peroxidase family: Discoveries and mechanism Molecular Medicine Reports

The PGAM5 gene is located on chromosome 12q24.33 and encodes a protein that was originally characterized as a mitochondrially localized Ser/Thr phosphatase

glutathione peroxidases in liver The peroxidase family: Discoveries and mechanism Molecular Medicine Reports

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