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They achieve this by regulating the differentiation of nave CD4 + T cells into specific T-helper (Th) subpopulations, such as Th1, Th2, and Th17, via the provision of co-stimulatory signals and the secretion of distinct cytokines (214, 269, 270)
Deficiency of H 2 S attenuates the immunosuppressive function of MSCs on colitis in vivo, while supplementation of NaHS can restore the impaired therapeutic effects 163
