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Kawakami, S

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Next to fundus examination, optical coherence tomography and fluorescein angiography are important diagnostic features [306]

biology Nicotinamide regulation Cellular signaling Enzyme function Cellular bioenergetics Methylation pathways Mechanism of Action 5-Amino-1MQ selectively inhibits the enzyme nicotinamide N-methyltransferase (NNMT), which plays a key role in nicotinamide utilization and cellular methylation pathways

FIGURE 3 FIGURE 4 AQP4 Was a Functional Target Gene of miRNA-146a-3p To investigate the reason of AQP4 decreased after GHK treatment, we predict the potential target microRNAs (miRNAs) of AQP4 (Supplementary Table 1) and got intersection elements with miRNAs down-regulated in ICH patients (Figure 5A)