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57 Although factors such as suboptimal sulfasalazine dosing and patient background may have limited its therapeutic effect, one patient achieved stable disease for over 4 months, In a phase I trial combining sulfasalazine with cisplatin and pemetrexed for advanced non-small cell lung cancer, the addition of sulfasalazine showed a response rate and progression-free survival (PFS) comparable to monotherapy

Acute intake of caffeine is associated with the acute elevation of blood pressure [88,107,108]