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However, the current clinical efficacy of these treatments remains heterogeneous, and there is a lack of personalized treatment protocols based on immune-inflammatory status, highlighting the need for further optimization of existing therapies

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10.1016/j.micpath.2024.106874

J., & Ali, A

had first described OFG as idiopathic persistent and/or recurrent labial enlargement, oral ulcers, and a spectrum of orofacial features with the absence of any other identifiable systemic conditions [3]