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Statistical difference between each theoretical ED 30 and its experimental ED 30 , along with confidence intervals for each dose ratio and its interaction indices, were calculated following the modified t-test proposed by [35], implemented in a homemade MATLAB script (available as supplementary material)

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To restore vitamin B12 levels and also fight vitamin b12 deficiency, administer half of the above doses and repeat at 12-week intervals, if necessary

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