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The aim of this study was to validate the effectiveness of scopolamine-treated animal models as POD experimental model, by identifying the change in inflammation-related cytokines and inflammasome components in various brain regions and candidate genes using RNA sequencing technology by comparing a scopolamine-induced delirium-like mice model and surgery mice

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
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Therefore, Yoshinori Ohsumi was awarded the Nobel Prize in Physiology or Medicine in 2016
