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To enhance cancer cell targeting, third-generation PSs are frequently integrated with NPs and additional therapeutic agents, including ferroptosis inducers

Klopp AH, Lacerda L, Gupta A, Debeb BG, Solley T, Li L, Spaeth E, Xu W, Zhang X, Lewis MT, Reuben JM, Krishnamurthy S, Ferrari M, Gaspar R, Buchholz TA, Cristofanilli M, Marini F, Andreeff M , Woodward WA

doi:10.1002/em.20361

USA 98 , 28492854 (2001)

Efficient screening of cytochrome P450 BM3 mutants for their metabolic activity and diversity toward a wide set of drug-like molecules in chemical space
