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Reactive oxygen species (ROS) may play an important role in activation of DCs [52] and increase the DC ability to activate CD4 + T cells [53]

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Ras-MAP kinase signaling by lysophosphatidic acid and other G protein-coupled receptor agonists Oncogene 20: 15401546, [PubMed] DOI: Pierce, KL, Luttrell, LM and Lefkowitz, RJ (2001)

Pink discoloration of the teeth and gums, an observation once thought to be a sign of drowning, is likely due to lividity in these tissues occurring while the body is in the aforementioned drowning position (6)

Timeline expectations based on mechanisms: Gene expression changes (GHK-Cu) occur within days but take weeks translating to measurable functional improvements