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ROS accumulation leading to an enhanced oxidative state is a key signature of plant responses to biotic and abiotic stresses such as drought, heat, salinity, and high light (Choudhury et al

Additional mitochondrial proteins such as glycine amidinotransferase, the redox-sensitive chaperone PARK7, peroxiredoxin 6, and the voltage-gated ion channel VDAC2 were found to be modified by NAPQI in 3D cultures of human hepatocytes and nonparenchymal cells29