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Nitrite bioactivation Inorganic nitrite is the conjugate base of nitrous acid, which has a much higher p K a [3.11 at 37C (da Silva et al ., 2006)] than nitric acid (conjugate acid of nitrate, p K a = 1.3), consistent with nitrite protonation under certain physiological circumstances such as in the low pH of the stomach and, thus, increased lipid solubility

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