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Indeed, Nrf2 expression can be regulated by SFN, that acting through cytoprotective enzymes with detoxifying and antioxidant action, such as nicotinamide adenine dinucleotide phosphate quinone oxidoreductase 1 (NQO-1), heme oxygenase 1 (HO-1), GSH S-transferase, and thioredoxin reductase, thus counteract the oxidative stress [10]
Collectively, these results suggest that ZDHHC11 serves as a palmitoyltransferase for ATG2A, facilitating S-palmitoylation at the C-terminus of ATG2A
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Without Catalent, the pathway to commercializing a single-chamber CagriSema could hit snags
