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In none of the included studies did a withdrawal or serious adverse event attributable to AOD-9604 occur. Research suggests this tolerability profile might support AOD-9604s relevance as a research tool for studying lipolytic mechanisms without confounding metabolic perturbations associated with full-length growth hormone

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Chronic myeloid leukemia, polycythemia vera, and hypereosinophilic syndrome are the classic associations, and the mechanism is thought to be overproduction of haptocorrin or transcobalamin by the expanded cell population