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It is also reported to be closely involved in the pathology of multiple sclerosis and other inflammatory diseases in the CNS [237]

USP22 also deubiquitinates RIPK3, which causes high hyperglycemia to trigger damage to podocyte intercellular collagenization while targeting USP22 increased the amount of ubiquitinated degradation of RIPK3 and protected podocytes[97]

Nonsense-mediated mRNA decay modulates clinical outcome of genetic disease

A regular sleep schedule and a calm bedtime routine can help improve sleep quality

[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Grant B.D., Donaldson J.G
