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[DOI] [PMC free article] [PubMed] [Google Scholar] 583.Chambers I.G., Ratan R.R

Consistent with these data, the qRT-PCR analysis also indicated that HPL administration (dose-dependent) significantly restored renal Ggt1 expression to the control levels, and a positive effect of HPL on Anpep expression was also observed

10.1016/j.bbamcr.2007.12.011 303 ShahheydariH.RagagninA.WalkerA

Review the evidence on hepatotoxicity, ALT/AST levels, and safe dosing protocols

The presence of two very good (and proven) brightening ingredients - niacinamide and the naturally-occurring glutathione in high concentrations, as well as licorice root extract (also brightening) and hyaluronic acid