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Description
Mitochondrial ROS can promote the oxidation of low-density lipoprotein (LDL) and proteins, causing damage to nuclear DNA and mitochondrial DNA in smooth muscle and endothelial cells
In recent years, increasing numbers of researchers have delved into this hotspot and found that the mechanisms included: secretion of growth factors such as BDNF [36, 37], neuroplasticity enhancement [38], improved brain oxygenation and nutrient supply [39], and reduced inflammation to protect neurons [40]

doi: 10.1111/acel.12379

doi: 10.1093/brain/awac270

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