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[(accessed on 21 April 2021)];Clin
J Am Geriatr Soc 2022;70(2):592600
To K, et al
used the rat pancreatic beta cell line Rin-5F to induce cell death via DM mimics, including high glucose, H 2 O 2 , and STZ, and reported that these factors accumulate ROS and iron, inactivate NRF2, and reduce the mitochondrial membrane potential, while treatment with Fer-1 mitigated these effects [87]
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