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It can activate the production of metalloproteinases and anti-proteases that remove damaged proteins from the extracellular matrix macromolecules

found that only during the reperfusion period, the expression of ferroptosis markers MDA and ACSL4 was significantly increased, accompanied by a down-regulation of GPX4 expression in the Sprague-Dawley rats (SD) model of IRI (Tang et al., 2021a)

Using this bacterium as a model, we identified a role for GR in intricately managing the balance of GSH and GSSG, which is essential for neutralizing ROS and protecting against oxidative cellular damage

Yuan D, Wu X, Gong B et al (2023) GABA metabolism, transport and their roles and mechanisms in the regulation of abiotic stress (hypoxia, salt, drought) resistance in plants