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These may arise indirectly from rapid weight loss-induced metabolic shifts, including nutrient and electrolyte depletion (e.g., magnesium, potassium, B-vitamins, iron), mitochondrial energy stress, and release of stored fat-soluble toxins (environmental chemicals, pesticides) into circulation during adipose tissue breakdown

doi: 10.1002/hep.31056 8 ChanM

Moreover, dietary diversity should be emphasized through increased consumption of fruits, vegetables, and whole grains, as these foods are rich in fiber, antioxidants, and micronutrients that help mitigate oxidative stress and lower the risk of chronic diseases

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