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Discovery of bisubstrate inhibitors of nicotinamide N -methyltransferase (NNMT)

However, there are no well-controlled studies in pregnant women, so this medication is generally recommended during pregnancy only when clearly needed

As with all compounds in this category, findings remain within the scope of controlled laboratory research

Riederer M, Erwa W, Zimmermann R, Frank S, Zechner R (2009) Adipose tissue as a source of nicotinamide N -methyltransferase and homocysteine

Hyperhomocysteinemia increases risk of metabolic syndrome and cardiovascular death in an elderly Chinese community population of a 7-year follow-up study