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Brain energy metabolizing enzymes in Alzheimer's disease: alpha-ketoglutarate dehydrogenase complex and cytochrome oxidase Ann N Y Acad Sci 1997

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Afc3 contains a C-terminal CBM51 and is the only fucosidase that contains a carbohydrate-binding module in C

To ascertain which KGDD is driving the observed phenotype, we constructed a CRISPR knockout library of 64 KGDDs and performed a dropout screen in the presence of olaparib (Fig