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In cancer biology and neurodegenerative disease, NNMT-driven SAM depletion alters epigenetic landscapes and gene expression patterns critical for cellular survival

It also prevents megaloblastic anemia, fatigue, and numbness or tingling in the hands and feet

[DOI] [PubMed] [Google Scholar] 19.Potential outcome factors in subacute combined degeneration: review of observational studies

30 Instead, off-target proteins like glutathione S -transferase omega-1, heme oxygenase 2, and thioredoxin domain containing 17 protein were identified

So an MMA result above range would indicate some problem in this area
