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Increased circulating IL-8 is associated with reduced IGF-1 and related to poor metabolic control in adolescents with type 1 diabetes mellitus

The tissue sections were then processed by blocking the endogenous peroxidase activity for 10 min, followed by incubation with primary antibodies

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Supplementing with B12 alone is typically targeted for specific deficiencies, whereas B complex is used for broader support of metabolic and cellular processes

These findings have resurrected the possibility that high folate status, or perhaps more specifically exposure to excess folic acid, may be harmful to people with low or deficient B12 status