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In the TME, macrophages can manifest as the M1 type (characterized by inflammatory and antitumour responses) or M2 type (involved in the repair of damaged tissues and anti-inflammation), but the TME tends to induce the differentiation of macrophages towards the M2 type (120122)

MPS III B (Sanfilippo B, stored heparan sulfate) using targeted enzyme replacement therapy with alpha-N- acetylglucosaminidase

Patients with liver disease often experience hyperbilirubinemia because their bodies arent breaking down bilirubin fast enough, leading to higher levels than normal

The specificity of CK1D1 and CK1D2 antibodies was first ascertained on lysates from PER2::LUC cells transfected with CK1D1 and CK1D2 described previoulsy 56 , shown in Fig

Funding Statement This work was supported by the National Natural Science Foundation of China (grant number: 82074085), the Natural Science Foundation of Zhejiang Province (grant number: LQ22H280008) and the Postgraduate Scientific Research Fund of Zhejiang Chinese Medical University (grant number: 2022YKJ20)