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A study found that sirtuin 3 SUMOylation increased the drug resistance of AML cells to AraC by up-regulating HES1-dependent FAO

Despite encouraging preclinical findings, clinical data are currently absent, and prioritization of early-phase human trials is necessary before any definitive conclusions can be drawn

doi: 10.1017/s0006323199005447 83 HeC.LiB.HuangL.TengC.BaoY.RenM.et al

Introduction Bacterial antimicrobial resistance (AMR) has become a major health threat due to the emergence and spread of multidrug-resistant (MDR) bacteria

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