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By inhibiting NNMT, 5-Amino-1MQ has been investigated for its potential to increase intracellular NAD+ levels and modulate lipid metabolism in preclinical settings

doi: 10.1007/s00401-015-1410-7 21 JacobKAlbrechtSSollierCFauryDSaderEMontpetitAet al

[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Lubrano V., Pingitore A., Traghella I., Storti S., Parri S., Berti S., Ndreu R., Andrenelli A., Palmieri C., Iervasi G., et al

3846) PCOOH and PEOOH concentrations were determined in microsomes and plasma membranes prepared from 2- and 17-month-old male SD rat hepatocytes, to verify the dissimilarity in age dependency of lipid peroxidation in organelle membranes