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Moxibustion therapy in traditional Mongolian medicine

Accordingly, by controlling the balance between glutamate uptake and release, astrocytes have the ability to maintain glutamate homeostasis, support normal neuronal function, and protect against glutamate excitotoxicity

10.1111/j.1432-1033.1988.tb13834.x 102 KlingerJ

All those effects cause relevant changes in glial cell regulation and inflammatory activation, triggering chronic neuroinflammation and potentiating pathological aging

When assessing drug efficacy for the treatment of glioblastoma multiforme (GBM), currently, the most reliable models are generated through direct injection of patient-derived cells or more frequently the isolation of glioblastoma cells endowed with stem-like features and orthotopically injecting these cells into the cerebrum of immunodeficient mice