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The role of cadaverine in the regulation of immune responses seems to be dependent on its concentration, at least in macrophages

10.16636/j.cnki.jinn.2014.04.015 28 GaoJ

Pattern recognition proteins (PRPs) like surfactant proteins A and D, mannose binding lectin, C1q, C-reactive protein, and IgM natural antibodies function as components of the innate immune system through the recognition of pathogen-associated molecular patterns (PAMPs) (e.g., RNA viruses) and damage-associated molecular patterns (DAMPs) (e.g., apoptotic cells) and subsequent facilitation of foreign particle clearance by alveolar macrophages and other macrophages in different tissues

(2) is PRP more effective than steroid to improve the foot and ankle function of plantar fasciitis patients? After reviewing twelve randomized controlled trials, involving 653 plantar fasciitis patients, the results showed that pain scores of the PRP group was significantly lower than that of the steroid group at 6-months, 1-year, and 1.5-year follow-up

The regulation of iron storage critically impacts ferroptosis: ferroptosis sensitivity can be significantly influenced by agents that reduce iron availability, such as the iron chelator deferoxamine, as well as by changes in iron-regulating proteins that modulate the cellular labile iron pool [3]
