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Eur Arch Otorhinolaryngol (2015) 272: 1119
Filtering removes the visible cloudiness by trapping aggregates, but you're left with a solution that contains far less peptide than the original concentration

The microbiome can also have an additive effect on oncotherapy

Ge HM Discovery and Biosynthesis of Guanipiperazine from a NRPS-like Pathway

That makes the combination easy to understand clinically, even while the final product remains investigational
