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Three structurally different classes of compounds considered to be of particular interest as starting points for the development of small-molecule IRAP inhibitors were identified

Synergistic Action: HA + GHK-Cu The combination of Hyaluronic Acid + GHK-Cu delivers a dual-action cosmetic effect : Hyaluronic Acid optimizes the skin environment, while GHK-Cu supports biological renewal signaling , making the serum effective for both instant results and cumulative benefits

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Bacterial contamination risk Bacteriostatic water's preservative effect diminishes over time

Primary outcomes included 90-day functional outcomes via ordinal regression of modified Rankin Scale (mRS) scores and recanalization rates