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Dysregulation of iron homeostasis mediated by FTH increases ferroptosis sensitivity in TP53-mutant glioblastoma

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Studies using human cell line lacking functional COQ6 showed impaired COQ synthesis, severe ATP deficiency, and increased production of reactive oxygen species [64]

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Long-term administration of berberine increases the expression of IL-1 and inducible nitric oxide synthase (iNOS) in Alzheimers disease mice hippocampus, and ameliorate memory impairment (Zhu and Qian, 2006)