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Treatment doses depend on the cause: pernicious anaemia typically requires intramuscular hydroxocobalamin 1,000 micrograms three times weekly initially, whilst dietary deficiency may be treated with oral cyanocobalamin 50150 micrograms or 1,000 micrograms daily

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These modifications make it more stable and resistant to enzymatic degradation compared to native GLP-1, allowing for prolonged activity in vitro and in vivo models
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