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Docking studies Docking studies of Cu(II)-TC-Py with a B-DNA dodecamer (PDB: 1BNA) was performed using AutoDock Vina 53

4.3 Consequences of mtDNA damage: from bioenergetic crisis to immune exhaustion mtDNA mutations and depletion impair the synthesis of essential ETC components, resulting in defective OXPHOS, reduced ATP synthesis, collapse of the mitochondrial membrane potential (m), and accumulation of metabolic intermediates due to TCA cycle disruption and compensatory glycolysis

(2020) Cannabidiol (CBD) as a promising anti-cancer drug

Abbreviations GGT: Gamma-glutamyl transferase H

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