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In laboratory testing, it did not inhibit related SAM-dependent methyltransferases or interfere with other enzymes in NAD+ salvage pathways

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Concurrently, alveolar epithelial cells, especially type I cells, undergo extensive shedding and necrosis, while type II epithelial cells fail to proliferate and restore a functional barrier, leading to alveolar septal rupture, alveolar cavity fusion, and even cystic changes or emphysematous alterations (188)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 149.Zeng Z, Yang D, Huang X, Xiao Z