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Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers

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Further reading: Vitamin B12 and Folic Acid The MTHFR Gene The critical stage in the folate cycle is the conversion of 5, 10-methylenetetrahydrofolate to 5-MTHF, which is then used in the methionine cycle

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