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Description
Mol Ther Nucleic Acids (2018) 11:45567

IGF-1 elevation is the primary mechanism through which full HGH increases the risk of insulin resistance, fluid retention, and certain growth-related effects at high doses

Using B12 injections outside clinical necessity exposes patients to unnecessary risks without proven benefit
Some patients must continue to take supplements or receive injections for life depending on the reason for the deficiency

As always, combination research should rest on a clear mechanistic rationale rather than simply stacking compounds
