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(2022c) used D-borneol and cisplatin to treat non-small cell lung cancer (NSCLC) cells resistant to cisplatin and discovered that it could shrink tumor volume and weight, enhance anti-tumor effect, promote ROS accumulation, stimulate ferritin uptake mediated by nuclear receptor co activator 4(NCOA4), and upregulate PRNP and downregulate PCBP2 to adjust intracellular iron transport to achieve ferroptosis