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Indeed, in hypoxic conditions heterozygous IDH1 -mutant cells were impeded in their reductive carboxylation ability and increased their oxidative TCA metabolism (Table 3)

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Emerging role of glycosylation in the polarization of tumor-associated macrophages
A recent study examined the efficacy of ibudilast to improve negative mood, reduce heavy drinking, and attenuate neural reward signals in individuals with AUD
