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Sus indicaciones principales son las crisis asmticas y el shock anafilctico

Biochemical evidence indicated that energy failure due to defects in oxidative phosphorylation altered vascular tone and prevented the recycling of reactive oxygen species, which are possible mechanisms responsible for triggering migraine headaches (141)

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Ogawa K, Kaizuma-Ueyama E, Hayashi M

Phenytoin competes with valproate for binding to albumin, potentially increasing the free level of valproate
