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The decreasing of osmoprotectants upon treatment with different TSCMZ concentrations may be related to the synergistic action between nanocomposite components, which enhance plant antioxidant capacity, that reduce the damage caused by oxidative stress and the requirements of protective osmolytes

FIGURE 1 While many essential steps of the sulfate assimilation and cysteine, methionine and glutathione biosynthesis pathways occur exclusively in plastids, a few enzymes present in the cytosol and mitochondria also come into play, which necessitates a concerted action between enzymes present in different subcellular compartments and intracellular transporters

Statistical analysis The number of case groups with MTHFR genotypes ( CC, CT, and TT genotypes) and the number of controls were extracted from our pooled studies