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Conophylline suppresses pancreatic stellate cells and improves islet fibrosis in Goto-Kakizaki rats

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doi: 10.3390/cancers15133427 252 WanQZouCHuDZhouJChenMTieCet al

In this review, we summarized various circadian misalignments, such as altered light-dark, sleep-wake, rest-activity, fasting-feeding, shift work, evening chronotype, and social jetlag, as well as mutations in clock genes that could contribute to the development of diabetes and poor glycemic status in patients with diabetes
