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Description
It protects liver, lung, and cardiac tissues from fibrosis and oxidative stress, as demonstrated in models of acute lung injury and cardiotoxicity
doi: 10.26355/eurrev_202002_20215 100
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Lessons from (S)-6-(1-(6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)ethyl)quinoline (PF-04254644), an inhibitor of receptor tyrosine kinase c-Met with high protein kinase selectivity but broad phosphodiesterase family inhibition leading to myocardial degeneration in rats
It does not replace medication , but it supports the system under metabolic pressure
