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nicotinic acetylcholine, glycine, GABA, and NMDA, AMPA, and kainate receptors) incorporate ion channels in their structures and mediate rapid responses

To improve neuronal survival and promote spine maturation, neuron-astrocyte co-culture systems were developed and refined where astrocytes provide tropic support ( Several groups have used modifications of this model to study the impact of AD stimulators, and prion disease-related neurodegeneration on the neuronal dendritic spine number and density ( in vitro platform of primary mouse neurons, following a modified bottom-up approach, to model the process of neuronal synaptic degeneration in the context of AD