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Because its topical rather than systemic, the risk profile differs from an injectable

Mohamed-Ahmed S, Fristad I, Lie SA, et al

10.1007/s11655-016-2407-3 107 LiH.LiD.MaZ.QianZ.KangX.JinX.et al (2018)

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The amlodipine-treated group exhibited normalization of all diastolic parameters but one (IVRT) (Figure 2D)