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(37) examined the effects of a H 2 /O 2 mixed gas (67% H 2 , 33% O 2 ) on patients with COVID-19 by an open-label multicenter clinical trial and showed that the improvements in disease severity, dyspnea, cough, chest distress, chest pain, and oxygen saturation were significantly greater in H 2 /O 2 treatment group (44 patients) than those in control group (46 patients)

Elipenahli C, Stack C, Jainuddin S, Gerges M, Yang L, Starkov A, Beal MF, Dumont M

Therefore, the interaction between oxidative stress and the HPA axis has become an vital focus in investigating the biological basis of PTSD