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nucleatum , a common pro-oncogenic bacterium in tumors, can activate the cGASSTING pathway, further leading to NF-B signaling activation and PD-L1 expression upregulation in tumor cells

This polarization, regulated by inflammatory signals, further contributes to neuroinflammation and exacerbates neuronal damage

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Aqua/Water/Eau, Glycerin, Caprylic/Capric Triglyceride, Butylene Glycol, Peg-240/Hdi Copolymer Bis-Decyltetradeceth-20 Ether, Limnanthes Alba (Meadowfoam) Seed Oil, Polyglyceryl-2 Diisostearate, Polysorbate 20, Butyrospermum Parkii (Shea) Butter Extract, Phenoxyethanol, Olea Europaea (Olive) Fruit Oil, Tocopheryl Acetate, Bisabolol, Cetearyl Olivate, Cyclopentasiloxane, Sorbitan Olivate, Caffeine, Panthenol, Propylene Glycol, Creatine, Dimethiconol, Salvia Hispanica Seed Oil, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Peg-8, Lecithin, Cyclohexasiloxane, Hydrogenated Lecithin, Ascorbyl Glucoside, Bht, Disodium Edta, Ginkgo Biloba Leaf Extract, Sodium Hydroxide, Tocopherol, Aesculus Hippocastanum (Horse Chestnut) Seed Extract, Glucose, Lactic Acid, Chlorphenesin, Alcohol Denat., Ascorbyl Palmitate, Pantolactone, Potassium Sorbate, Camellia Sinensis Leaf Extract, Coffea Arabica (Coffee) Seed Extract, Pongamia Pinnata Seed Extract, Sorbic Acid, Citric Acid, Ascorbic Acid, Sodium Benzoate, Angelica Archangelica Root Extract, Citrus Aurantium Amara (Bitter Orange) Peel Extract, Maltodextrin, Polyglyceryl-3 Diisostearate, Magnesium Aluminum Silicate, Xanthan Gum, Farnesol, Caprylyl Glycol, Sclerotium Gum, Fd&Amp;C Yellow No

College of Food, Northeast Agricultural University, China) was added to 0.9 ml buffer solution with different pH levels