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225 This class includes the F508del mutation, which is the most frequent variant detected in CF and gives rise to a CFTR protein that exhibits defects in channel gating properties, 226 as well as increased retention in the ER followed by degradation by the ubiquitinproteasome system (UPS)

Plantas y activos asociados Nombre comn Glutatin reducido Nombre cientfico GSH Preguntas frecuentes Comprados juntos habitualmente Opiniones de los clientes

doi: 10.1007/s12035-016-0079-9 107 van HerwaardenAEWagenaarEMerinoGJonkerJWRosingHBeijnenJHet al

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