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Non-genetic mechanisms have recently emerged as important drivers of anticancer drug resistance

PubMed Central, doi:10.1016/j.coph.2007.04.005

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Activation of mitochondrial voltage-dependent anion channels and mitogen-activated protein kinases, upregulation of endoplasmic reticulum stress, and inhibition of cystine/glutamate antiporter is involved in the induction of ferroptosis