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Anderson KA, Lin F, Ribar TJ, Stevens RD, Muehlbauer MJ, Newgard CB, et al

A multicenter, double blind RCT that included 332 patients with inflammatory acne demonstrated that minocycline hydrochloride treatment was superior to oral zinc gluconate regarding improvement in superficial inflammatory count and comedone count after three months of use

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doi: 10.1093/jnci/93.4.266 44 YuLChenXWangLChenS

Since hair follicle apoptosis occurs during catagen and the activity of the hair follicle is minimized during telogen [33], our study proposes a new principle that mitophagy maintains intracellular mitochondrial homeostasis and repairs the cell through selective self-elimination of the damaged mitochondria accumulated during catagen and telogen, thus is required for hair regeneration