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Thats the point of having an independent advisory committee, he said

However, the powder must be reconstituted (dissolved back into liquid form) before it can be used in research applications
This is often the case with people with disorders such as IBS or inflammatory bowel diseases (Crohns / ulcerative colitis) or those who have undergone weight loss surgery

The transition from observing natural NPY as a biomarker to using exogenous NPY as a treatment involves assumptions about dose-response relationships that have not been fully validated in human trials
